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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1990-2-20
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pubmed:abstractText |
The pattern of glucose metabolism in the glomerular layer of the main olfactory bulb was studied in rats trained to sample brief odor stimuli. After injection with [14C]2-deoxyglucose (2-DG). 5 rats were tested for discrimination of propionic acid from air. Over the 45 min test period rats sampled the stimulus for 0.5-0.8s during each trial and their total exposure to the stimulus was 53-147 s. A discrete focus of increased glucose metabolism was found in the central dorsomedial sector of the glomerular layer in each animal. The position of this focus and the overall pattern of glomerular layer activity was essentially identical to that obtained in 4 control rats which were exposed passively to alternating 5 min periods of the odor and clean air for 45 min. The size of the primary focus was only slightly smaller in the trained rats, despite the large difference in total exposure time. The absence of olfactory adaptation during the behavioral tests and the similar pattern of 2-DG uptake in controls and trained animals indicate that adaptation does not play a significant role in the patterns of glucose metabolism induced in the glomeruli of the olfactory bulb by extended exposure to an odor.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Deoxy Sugars,
http://linkedlifedata.com/resource/pubmed/chemical/Deoxyglucose,
http://linkedlifedata.com/resource/pubmed/chemical/Propionates,
http://linkedlifedata.com/resource/pubmed/chemical/Propionic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/propionic acid
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
500
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2605489-Animals,
pubmed-meshheading:2605489-Autoradiography,
pubmed-meshheading:2605489-Deoxy Sugars,
pubmed-meshheading:2605489-Deoxyglucose,
pubmed-meshheading:2605489-Discrimination Learning,
pubmed-meshheading:2605489-Male,
pubmed-meshheading:2605489-Odors,
pubmed-meshheading:2605489-Olfactory Bulb,
pubmed-meshheading:2605489-Propionates,
pubmed-meshheading:2605489-Propionic Acids,
pubmed-meshheading:2605489-Rats,
pubmed-meshheading:2605489-Rats, Inbred Strains
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pubmed:year |
1989
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pubmed:articleTitle |
Odor-induced metabolic activity in the olfactory bulb of rats trained to detect propionic acid vapor.
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pubmed:affiliation |
Department of Psychology, American University, Washington, D.C. 20016.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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