Linked Life Data

2604818

Source:http://linkedlifedata.com/resource/pubmed/id/2604818

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1990-2-15
pubmed:abstractText
During the early development of the acoustic system a conductive hearing loss may alter the maturation of acoustically evoked potentials and affect the development of hearing. The present experiments were carried out in newborn guinea pigs with binaural conductive hearing loss. The external ear canals were plugged over a period of one month from the first day postpartum. During and after deprivation click-evoked Auditory Brainstem Responses (ABR) and Middle Latency Responses (MLR) were collected to analyze changes in the maturation of these potentials in comparison to untreated animals. This type of deprivation is characterized by threshold elevations of about 40 dB over a wide frequency range. In young deprived animals, ABR Latencies (PIII, PV) and interpeak latencies exhibited a significant delay with a maximum between day 13 and 19, which disappeared within 10 days after the end of the treatment. MLR latencies were also significantly affected after three to four weeks of the deprivation phase. In contrast to the ABR, the recovery of the latencies was completed within four to six weeks. These results therefore indicate that a conductive hearing loss may alter the maturation of the acoustically evoked responses in the sensitive phase after birth. This type of partial deprivation may affect the development of hearing and speech perception in children with chronically occurring otitis media.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0935-8943
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
626-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Effect of binaural conductive hearing loss on maturation of acoustically evoked potentials (auditory brain stem response, middle latency response) in guinea pigs].
pubmed:affiliation
Universitäts-HNO-Klinik Köln.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't