Linked Life Data

2603560

Source:http://linkedlifedata.com/resource/pubmed/id/2603560

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-1-26
pubmed:abstractText
The aim of the work was the modelling in vitro of the condition of increased afferent inflow, which in the intact septum results in an increase of population of theta-bursting units, their synchronization and shift to a higher frequency of the bursts, with corresponding changes in the hippocampal electrical activity. Neuronal activity was recorded extracellularly in the medial septal nucleus and vertical limb of the nucleus of diagonal band (MS-DB) in guinea pig septal slices. Electrical stimulation in the medial part of horizontal limb of DB evokes initial period of suppression of spontaneous activity in 85% of the neurones. This low-threshold, rapid inhibition has variable duration (20-280 ms) in different units at low intensities of the stimulating current. With increased intensities of stimulation this inhibitory phase in majority of units is gradually or by steps shortened, though in some units with initial short inhibition it is not changed. As a result the variability of initial inhibitory period between units is decreased and centered around 30-60 ms. Many units with single-spike background activity developed postinhibitory burst responses at various levels of stimulating current. The spontaneously bursting MS-DB units always responded by resetting of their background bursts. In total 58% of all recorded neurones generated evoked bursts under condition of increased afferent inflow.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0044-4677
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
924-34
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[The modelling of theta rhythm regulation by an increasing afferent inflow in septal slices in vitro].
pubmed:publicationType
Journal Article, English Abstract