Linked Life Data

2602938

Source:http://linkedlifedata.com/resource/pubmed/id/2602938

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1990-2-2
pubmed:abstractText
Exploratory studies were conducted to determine if chromium from Whetlerite dust is bioavailable when administered intratracheally to rats, and if so, to determine its speciation. These studies indicated that chromium in this form and by this route of administration was bioavailable and was found in the trivalent state only. Less than 25% of the administered dose was recovered after 4 h, suggesting that most of the chromium was rapidly absorbed, distributed, and eliminated. Most of the chromium was found in the lungs and kidneys. The time course in the kidney suggests that this organ may be involved in the metabolism and elimination of trivalent chromium. Unexpected mortality in the experimental group of rats may have been due to the copper content of the Whetlerite, which exceeded the LD50 in the dose administered.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0048-9697
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
59-64
pubmed:dateRevised
2006-4-19
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Speciation, bioavailability, and systemic distribution of chromium from Whetlerite dust.
pubmed:affiliation
Chemistry Research, Development, and Engineering Center, Aberdeen Proving Ground, MD 21010-5423.
pubmed:publicationType
Journal Article