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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
24
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pubmed:dateCreated |
1990-2-1
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pubmed:abstractText |
Molecular dynamics simulations were coupled with experimental data from biochemistry and genetics to generate a theoretical structure for the binding domain of Hin recombinase complexed with the hix site of DNA. The theoretical model explains the observed sequence specificity of Hin recombinase and leads to a number of testable predictions concerning altered sequence selectivity for various mutants of protein and DNA.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9841-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2602378-Amino Acid Sequence,
pubmed-meshheading:2602378-Base Sequence,
pubmed-meshheading:2602378-Binding Sites,
pubmed-meshheading:2602378-DNA,
pubmed-meshheading:2602378-DNA Nucleotidyltransferases,
pubmed-meshheading:2602378-Models, Molecular,
pubmed-meshheading:2602378-Molecular Sequence Data,
pubmed-meshheading:2602378-Nucleic Acid Conformation,
pubmed-meshheading:2602378-Protein Binding,
pubmed-meshheading:2602378-Structure-Activity Relationship,
pubmed-meshheading:2602378-Substrate Specificity
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pubmed:year |
1989
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pubmed:articleTitle |
Predictions of structural elements for the binding of Hin recombinase with the hix site of DNA.
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pubmed:affiliation |
Arthur Amos Noyes Laboratory of Chemical Physics, California Institute of Technology, Pasadena 91125.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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