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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1990-2-2
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pubmed:abstractText |
We investigated the incidence and characteristics of an elevated tumor associated antigen CA 19-9 in patients with rheumatic diseases. Serum concentration of CA 19-9 was increased in 13 of 39 patients (33.3%) with definite or classical rheumatoid arthritis (RA), in 6 of 19 patients (31.6%) with systemic lupus erythematosus (SLE), in 3 of 9 patients (33.3%) with progressive systemic sclerosis (PSS) and in 9 of the other 35 patients (25.7%). Malignant neoplasm was not detected in any of the patients with rheumatic diseases. Pretreatment of mouse serum with patients' sera did not reduce the measured CA 19-9 values obtained by the conventional assay. The CA 19-9 antigen found in sera from patients with RA was present in a non-IgG fraction, and had the same molecular weight as that in one patient with pancreatic cancer, as determined by gel filtration. These results demonstrated that serum CA 19-9 levels were increased in some patients with rheumatic diseases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
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pubmed:issn |
0315-162X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
|
pubmed:pagination |
1410-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2600938-Adult,
pubmed-meshheading:2600938-Aged,
pubmed-meshheading:2600938-Aged, 80 and over,
pubmed-meshheading:2600938-Amyloidosis,
pubmed-meshheading:2600938-Antigens, Tumor-Associated, Carbohydrate,
pubmed-meshheading:2600938-Behcet Syndrome,
pubmed-meshheading:2600938-Collagen Diseases,
pubmed-meshheading:2600938-Female,
pubmed-meshheading:2600938-Humans,
pubmed-meshheading:2600938-Immunoglobulin G,
pubmed-meshheading:2600938-Male,
pubmed-meshheading:2600938-Middle Aged,
pubmed-meshheading:2600938-Neoplasms,
pubmed-meshheading:2600938-Radioimmunoassay,
pubmed-meshheading:2600938-Severity of Illness Index
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pubmed:year |
1989
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pubmed:articleTitle |
Elevation of a tumor associated antigen CA 19-9 levels in patients with rheumatic diseases.
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pubmed:affiliation |
First Department of Internal Medicine, Nagasaki University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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