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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
1990-2-2
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pubmed:abstractText |
Among 72 patients with the Peutz-Jeghers syndrome malignant tumours have developed in 16 (22%) of whom all but one have died. There were nine gastrointestinal and seven nongastrointestinal tumours. The relative risks of death from gastrointestinal cancer and all cancers were 13 (95% CI 2.7-38.1) and 9 (95% CI 4.2-17.3) respectively. The chance of dying of cancer by the age of 57 was 48%. There is evidence for a hamartoma/carcinoma sequence in the Peutz-Jeghers syndrome, suggesting that the gene locus involved is relevant to the development of malignancy in general.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-1117595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-15398245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-3040875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-348556,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-3587280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-4407824,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-6479688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-6770991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-6837833,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-7059931,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-7093914,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-7104978,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2599445-7187092
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0017-5749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1588-90
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1989
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pubmed:articleTitle |
Cancer and the Peutz-Jeghers syndrome.
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pubmed:affiliation |
St Mark's Hospital, London.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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