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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1990-1-26
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pubmed:abstractText |
By means of 3 endurance exercises, the effect of a several-hour intensive somatic stress on the changes of the Sm-C/IGF-I concentration was tested during, immediately after and on the day following the exercise. Exp. 1: Marathon with 17 male sportsmen in 2 groups with different glucose supply. Exp. 2: 45-km crosscountry run with 41 males. Exp. 3: Three 20-km runs with 8 young females at intervals of 3 months. In the marathon, no significant changes of the Sm-C/IGF-I concentration were found between the start, half distance and final values. The exogenous glucose supply (continuous or discontinuous) had also no effect. The tendency of a slight decrease of the Sm-C/IGF-I concentration by 0.14 U/ml (p greater than 0.05) was observed between start and finish in the 45 km crosscountry run lasting one hour longer. In the three 20-km runs, reproducible, slightly increased levels were measured at the end, whereas a decrease to the initial value or even below was detected on the following day (p greater than 0.05). The insignificant alterations of the Sm-C/IGF-I concentration measured in the 3 variants of races show that neither the hormonal changes stimulating the Sm-C/IGF-I synthesis (e.g. increase of GH and prolactin) nor inhibiting factors (energy deficiency) clearly dominate during strenuous exercises. The binding of carrier protein prevents great variations of the Sm-C/IGF-I level even under the condition of 3- to 4-hour extreme endurance exercises.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0232-7384
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
89-96
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2599025-Adolescent,
pubmed-meshheading:2599025-Adult,
pubmed-meshheading:2599025-Female,
pubmed-meshheading:2599025-Humans,
pubmed-meshheading:2599025-Insulin-Like Growth Factor I,
pubmed-meshheading:2599025-Male,
pubmed-meshheading:2599025-Physical Endurance,
pubmed-meshheading:2599025-Running,
pubmed-meshheading:2599025-Sex Factors,
pubmed-meshheading:2599025-Somatomedins,
pubmed-meshheading:2599025-Stress, Physiological
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pubmed:year |
1989
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pubmed:articleTitle |
Effect of endurance exercise on somatomedin-C/insulin-like growth factor I concentration in male and female runners.
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pubmed:affiliation |
Children's Hospital, Friedrich-Schiller-University, Jena, GDR.
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pubmed:publicationType |
Journal Article
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