Linked Life Data

2598644

Source:http://linkedlifedata.com/resource/pubmed/id/2598644

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1990-1-29
pubmed:abstractText
Human factor D was purified, labelled with 125I and injected intracardially or intraperitoneally into male Sprague-Dawley rats. After intracardial administration, 80% of the radioactivity seen initially in the blood was eliminated within 5 min. The highest levels of radioactivity were recovered in the kidney cortex in both cases: maximally 24% of the total dose applied was recovered in this tissue 7 min after intracardial injection and 8-9% of the total dose 80-90 min after intraperitoneal administration. Significant amounts of radioactivity were also observed in the spleen, lungs, liver and heart muscle, but uptake by other tissues was very low. These results indicated that injected human factor D disappeared rapidly from the plasma of rats and uptake by the kidney cortex was one of the main routes of elimination.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1012-8204
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
453-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Tissue distribution of radiolabelled human factor D in the male Sprague-Dawley rat.
pubmed:affiliation
Department of Medical Microbiology, University of Lund, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't