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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions |
umls-concept:C0005821,
umls-concept:C0015354,
umls-concept:C0026336,
umls-concept:C0030068,
umls-concept:C0039005,
umls-concept:C0180860,
umls-concept:C0221464,
umls-concept:C0303403,
umls-concept:C0581406,
umls-concept:C1517945,
umls-concept:C1522485,
umls-concept:C1522664,
umls-concept:C1546637,
umls-concept:C1550638,
umls-concept:C1704449,
umls-concept:C1704684,
umls-concept:C1708632,
umls-concept:C1709793
|
| pubmed:issue |
3
|
| pubmed:dateCreated |
1990-2-6
|
| pubmed:abstractText |
Platelet consumption in a hollow-fiber membrane oxygenator (HFMO) and arterial filter (AF) during cardiopulmonary bypass (CPB) was quantified in five pigs using Indium-111 labeled autologous platelets. Platelet labeling was performed 20-24 hours before CPB. After general endotracheal anesthesia, the pigs were systemically heparinized and were placed on CPB via a median sternotomy. After 3 hours of CPB, radioactivity was quantified with a gamma camera and an ionization chamber. The percent of injected dose (mean +/- SD) was 0.79 +/- 0.45 in the HFMO, 2.52 +/- 0.93 in AF, 4.3 +/- 1.2 in blood loss during CPB. Platelet consumption in HFMO during CPB was lower than in bubble oxygenators (19%) or silicone membrane oxygenators (12%) as observed in previous studies.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0889-7190
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
35
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
667-70
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2597560-Animals,
pubmed-meshheading:2597560-Blood Platelets,
pubmed-meshheading:2597560-Equipment Design,
pubmed-meshheading:2597560-Female,
pubmed-meshheading:2597560-Hemofiltration,
pubmed-meshheading:2597560-Indium Radioisotopes,
pubmed-meshheading:2597560-Organometallic Compounds,
pubmed-meshheading:2597560-Oxygenators, Membrane,
pubmed-meshheading:2597560-Platelet Count,
pubmed-meshheading:2597560-Swine,
pubmed-meshheading:2597560-Thrombocytopenia,
pubmed-meshheading:2597560-Tropolone
|
| pubmed:articleTitle |
Quantitation of platelet loss with indium-111 labeled platelets in a hollow-fiber membrane oxygenator and arterial filter during extracorporeal circulation in a pig model.
|
| pubmed:affiliation |
Divisions of Thoracic and Cardiovascular Surgery, University of Miami School of Medicine, FL 33101.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|