rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1990-2-6
|
pubmed:abstractText |
A multicomparative study to establish adequate anticoagulation therapy for left ventricular assist devices was undertaken by administrating various anticoagulants: heparin, a prostacyclin analogue combined with a protease inhibitor; thromboxane A2 synthetase inhibitor; or a protease inhibitor alone. Our investigation suggested that combined administration of prostacyclin analogue and protease inhibitor (FUT-175) is ideal anticoagulation therapy from the point of blood coagulation and fibrinolysis. Currently, however, sole administration of FUT-175 is adequate anticoagulation therapy during clinical use of left ventricular assist devices.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0889-7190
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
35
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
426-9
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:2597495-Anticoagulants,
pubmed-meshheading:2597495-Blood Coagulation Tests,
pubmed-meshheading:2597495-Factor XII,
pubmed-meshheading:2597495-Fibrinogen,
pubmed-meshheading:2597495-Guanidines,
pubmed-meshheading:2597495-Heart-Assist Devices,
pubmed-meshheading:2597495-Heparin,
pubmed-meshheading:2597495-Humans,
pubmed-meshheading:2597495-Methacrylates,
pubmed-meshheading:2597495-Platelet Aggregation,
pubmed-meshheading:2597495-Platelet Aggregation Inhibitors,
pubmed-meshheading:2597495-Platelet Count,
pubmed-meshheading:2597495-alpha-2-Antiplasmin
|
pubmed:articleTitle |
Significance of various anticoagulation therapies during use of a left ventricular assist device.
|
pubmed:affiliation |
First Department of Surgery, Saitama Medical Center, Saitama Medical College, Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|