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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1990-1-11
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pubmed:abstractText |
Application for myocardial imaging and fundamental experiments were studied using straight chain fatty acid analog IPPA [omega-(p-iodophenyl)-pentadecanoic acid]. Biodistribution of IPPA in rabbits (n = 6) shows the accumulation in liver was maintained 81.0% at 30 minutes, while the accumulations of heart, lungs and kidneys were 30.0%, 10.0% and 15.0% respectively. Especially the accumulation of heart decreased rapidly from 48.0% at 3 minutes to 30.0% at 30 minutes, reflecting the effect of beta oxidation. On the other hand, in the acute myocardial infarction mode (n = 6), with occlusion in left anterior descending coronary artery, all 6 cases showed defect images at the corresponding areas after injection of 3 mCi of IPPA. Myocardial imaging with IPPA should be useful not only for myocardial metabolic diseases (cardiomyopathy etc.) but also for ischemic heart disease.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-7854
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
1295-301
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2585843-Animals,
pubmed-meshheading:2585843-Iodine Radioisotopes,
pubmed-meshheading:2585843-Iodobenzenes,
pubmed-meshheading:2585843-Male,
pubmed-meshheading:2585843-Myocardial Infarction,
pubmed-meshheading:2585843-Myocardium,
pubmed-meshheading:2585843-Rabbits,
pubmed-meshheading:2585843-Tissue Distribution
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pubmed:year |
1989
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pubmed:articleTitle |
[Application of straight chain fatty acid analog IPPA [omega-(p-iodophenyl)-pentadecanoic acid] for myocardial imaging--using acute myocardial infarction model].
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pubmed:publicationType |
Journal Article,
English Abstract
|