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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1990-1-11
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pubmed:abstractText |
The possible association between HLA-DR4 and interleukin 1 beta (IL-1 beta) secretion from peripheral blood monocytes was analyzed using 34 female patients, with definite rheumatoid arthritis (RA). RA monocytes in serum-free medium or medium supplemented with 10% fetal calf serum secreted IL-1 spontaneously. The level of secretion was enhanced by stimulation with pyrogen-free type II collagen as determined by comparison with 30 healthy individuals matched for age and sex. No association between HLA-DR4 and spontaneous or stimulated IL-1 release from RA monocytes was observed.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0315-162X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1025-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2585399-Adult,
pubmed-meshheading:2585399-Arthritis, Rheumatoid,
pubmed-meshheading:2585399-Cells, Cultured,
pubmed-meshheading:2585399-Collagen,
pubmed-meshheading:2585399-Female,
pubmed-meshheading:2585399-HLA-DR4 Antigen,
pubmed-meshheading:2585399-Humans,
pubmed-meshheading:2585399-Interleukin-1,
pubmed-meshheading:2585399-Middle Aged,
pubmed-meshheading:2585399-Monocytes,
pubmed-meshheading:2585399-Serum Albumin, Bovine,
pubmed-meshheading:2585399-Severity of Illness Index
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pubmed:year |
1989
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pubmed:articleTitle |
Lack of association of HLA-DR4 with interleukin 1 beta secretion from peripheral blood monocytes in patients with rheumatoid arthritis.
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pubmed:affiliation |
Division of Rheumatic Diseases, Tokyo Metropolitan Otsuka Hospital, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|