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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1985-7-12
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pubmed:abstractText |
Experimental allergic neuritis (EAN) was induced in normal Lewis rats by systemic passive transfer of T-cell lines responding to P2 protein. These cells had predominantly helper phenotype and could induce EAN within 7 days following adoptive transfer. There was no anti-P2 antibody response in the recipients of the P2-reactive cells recovered from donors with high anti-P2 antibody levels. This study provides direct evidence that T cells are important for the induction of EAN. Furthermore, there was no evidence of a pathogenic role for anti-P2 antibody in passive EAN.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0008-8749
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
354-61
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2581699-Animals,
pubmed-meshheading:2581699-Antigens,
pubmed-meshheading:2581699-Cell Line,
pubmed-meshheading:2581699-Immunization, Passive,
pubmed-meshheading:2581699-Male,
pubmed-meshheading:2581699-Myelin Basic Proteins,
pubmed-meshheading:2581699-Myelin P2 Protein,
pubmed-meshheading:2581699-Neuritis, Autoimmune, Experimental,
pubmed-meshheading:2581699-Rats,
pubmed-meshheading:2581699-Rats, Inbred Lew,
pubmed-meshheading:2581699-T-Lymphocytes,
pubmed-meshheading:2581699-T-Lymphocytes, Helper-Inducer
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pubmed:year |
1985
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pubmed:articleTitle |
Transfer of experimental allergic neuritis with P2-reactive T-cell lines.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|