Linked Life Data

2581509

Source:http://linkedlifedata.com/resource/pubmed/id/2581509

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1985-6-20
pubmed:abstractText
The studies were performed on CBA mice. It was shown that polynucleotide inductors (poly I-poly C, RFf2 and poly G-poly C) stimulated production of interferon with a peak attained 4-6 or 24 hours after the induction. Intraperitoneal injection of dextran sulfate in a dose of 200 micrograms/m induced production of interferon in small amounts (80-120 units). The production peak was observed in 12 hours. The combined use of dextran sulfate and the polynucleotide inductors provoked an increase in the interferon production. The effect was of a synergistic nature. The cells of the immunocompetent system were the target of the dextran sulfate effect in the host, which was shown experimentally with a culture of mouse lymphocytes.
pubmed:language
rus
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:author
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
16-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Effect of the combined use of dextran sulfate and double-stranded RNA on interferon production].
pubmed:publicationType
Journal Article, In Vitro, English Abstract