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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1985-4-25
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pubmed:abstractText |
In the present report we provide the strain distribution patterns of susceptibility to acute mouse hepatitis virus type-4 (MHV-4) encephalomyelitis, acute experimental allergic encephalomyelitis (EAE) and vasoactive amine sensitivity (VAAS) for 9 (CXJ) recombinant-inbred strains between BALB/cKe (C) and SJL/J(J) mice. We confirm that susceptibility to MHV-4 is not linked to the H-2 complex, and that all strains susceptible to acute EAE have both a responder H-2 haplotype (H-2s or H-2d) and induced (B. pertussis) VAAS. In addition, we provide evidence that susceptibility to acute EAE induction is controlled by an additional presently unmapped locus and that an EAE-like histopathological disease does not usually follow MHV-4 infection intracerebrally in animals susceptible to MHV-4, acute EAE and induced VAAS.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0165-5728
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-28
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2579095-Animals,
pubmed-meshheading:2579095-Bordetella pertussis,
pubmed-meshheading:2579095-Drug Hypersensitivity,
pubmed-meshheading:2579095-Encephalomyelitis,
pubmed-meshheading:2579095-Encephalomyelitis, Autoimmune, Experimental,
pubmed-meshheading:2579095-Female,
pubmed-meshheading:2579095-H-2 Antigens,
pubmed-meshheading:2579095-Haploidy,
pubmed-meshheading:2579095-Hepatitis, Viral, Animal,
pubmed-meshheading:2579095-Histamine,
pubmed-meshheading:2579095-Humans,
pubmed-meshheading:2579095-Immunity, Innate,
pubmed-meshheading:2579095-Male,
pubmed-meshheading:2579095-Mice,
pubmed-meshheading:2579095-Mice, Inbred Strains,
pubmed-meshheading:2579095-Murine hepatitis virus,
pubmed-meshheading:2579095-Myelin Basic Proteins,
pubmed-meshheading:2579095-Rats
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pubmed:year |
1985
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pubmed:articleTitle |
Host genetic regulation of acute MHV-4 viral encephalomyelitis and acute experimental autoimmune encephalomyelitis in (BALB/cKe x SJL/J) recombinant-inbred mice.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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