rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8676
|
pubmed:dateCreated |
1990-1-17
|
pubmed:abstractText |
The polymerase chain reaction was used to amplify a Y-specific repeat sequence in peripheral blood DNA samples from 19 pregnant women who had a gestational age of 9 to 41 weeks. Y-specific sequences were amplified from all 12 women who bore a male fetus but in none of 7 women who bore a female fetus. With stringent precautions against contamination, this technique may assist prenatal diagnosis of sex-linked genetic disorders.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0140-6736
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
9
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1363-5
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:2574306-Blood,
pubmed-meshheading:2574306-Female,
pubmed-meshheading:2574306-Fetus,
pubmed-meshheading:2574306-Gene Amplification,
pubmed-meshheading:2574306-Genetic Markers,
pubmed-meshheading:2574306-Humans,
pubmed-meshheading:2574306-Male,
pubmed-meshheading:2574306-Polymerase Chain Reaction,
pubmed-meshheading:2574306-Pregnancy,
pubmed-meshheading:2574306-Sex Determination Analysis,
pubmed-meshheading:2574306-Y Chromosome
|
pubmed:year |
1989
|
pubmed:articleTitle |
Prenatal sex determination by DNA amplification from maternal peripheral blood.
|
pubmed:affiliation |
University of Oxford Clinical School.
|
pubmed:publicationType |
Journal Article
|