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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1990-1-11
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pubmed:abstractText |
We report the physical linkage of the gene encoding one of the subunits of the GABAA receptor (GABRA3) to the polymorphic locus DXS374 on the human X chromosome at Xq28. X-linked manic depression and other psychiatric disorders have been mapped to this region, and thus GABRA3 is a potential candidate gene for these disorders. DXS374--and therefore GABRA3--lies distal to the fragile X locus at a recombination fraction of approximately .15.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-2501212,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-2565870,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-2744766,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-2842688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-2851368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-2884369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-2888146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-2937147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-2995646,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-3026644,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-3037384,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-3154515,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-3482420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-3493438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-3507278,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-3515319,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-3538420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2574000-6438525
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0002-9297
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
883-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:2574000-DNA Probes,
pubmed-meshheading:2574000-Genetic Linkage,
pubmed-meshheading:2574000-Genetic Markers,
pubmed-meshheading:2574000-Humans,
pubmed-meshheading:2574000-Mental Disorders,
pubmed-meshheading:2574000-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:2574000-Receptors, GABA-A,
pubmed-meshheading:2574000-Restriction Mapping,
pubmed-meshheading:2574000-X Chromosome
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pubmed:year |
1989
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pubmed:articleTitle |
Physical linkage of a GABAA receptor subunit gene to the DXS374 locus in human Xq28.
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pubmed:affiliation |
Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, England.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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