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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1989-11-20
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pubmed:abstractText |
Sixty-eight asymptomatic HIV-seropositive people with a CD4 lymphocyte count above 400/mm3 at the first examination were followed up every year over a 3-year period, by monitoring the biological markers of AIDS (CD4 lymphocyte decrease, loss of anti-p24 or anti-p17 antibodies, positive p24 antigenemia, increase of erythrocyte sedimentation rate, and of serum levels of immunoglobulin G. immunoglobulin A, neopterin and beta 2-microglobulin). The percentages of subjects positive for at least one marker at the first, second, third and fourth examinations were 66, 88, 94 and 97%, respectively. The increase in the number of markers with time was significant (chi-square test; P less than 0.001). This increase suggests a progression to AIDS in the majority of asymptomatic seropositive subjects, even those without a decreased CD4 lymphocyte count.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0269-9370
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
603-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2571349-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:2571349-Adult,
pubmed-meshheading:2571349-Biological Markers,
pubmed-meshheading:2571349-CD4-Positive T-Lymphocytes,
pubmed-meshheading:2571349-Chi-Square Distribution,
pubmed-meshheading:2571349-Cohort Studies,
pubmed-meshheading:2571349-Female,
pubmed-meshheading:2571349-HIV Antibodies,
pubmed-meshheading:2571349-HIV Antigens,
pubmed-meshheading:2571349-HIV Infections,
pubmed-meshheading:2571349-HIV Seropositivity,
pubmed-meshheading:2571349-Humans,
pubmed-meshheading:2571349-Male,
pubmed-meshheading:2571349-Prognosis,
pubmed-meshheading:2571349-Risk Factors,
pubmed-meshheading:2571349-Time Factors
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pubmed:year |
1989
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pubmed:articleTitle |
Progression to AIDS in the majority of asymptomatic HIV-infected people.
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pubmed:affiliation |
Institut National de Transfusion Sangvine, Paris, France.
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pubmed:publicationType |
Journal Article
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