| pubmed-article:2571199 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2571199 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2571199 | lifeskim:mentions | umls-concept:C0031307 | lld:lifeskim |
| pubmed-article:2571199 | lifeskim:mentions | umls-concept:C0015982 | lld:lifeskim |
| pubmed-article:2571199 | lifeskim:mentions | umls-concept:C1149592 | lld:lifeskim |
| pubmed-article:2571199 | lifeskim:mentions | umls-concept:C1513475 | lld:lifeskim |
| pubmed-article:2571199 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2571199 | pubmed:dateCreated | 1989-10-20 | lld:pubmed |
| pubmed-article:2571199 | pubmed:abstractText | The physiologic function of the monocyte transglutaminases is not known. In this study, we detected Factor XIII A-subunit antigen and "tissue" transglutaminase antigen in human monocytes by polyacrylamide gel electrophoresis and immunoblotting techniques. Flow cytometric analysis demonstrated that 27% and 49% of the total Factor XIII antigen in monocytes and human peritoneal macrophages, respectively, are expressed on the surface of the cells. Monocytes maintained in culture for 8 days had a 4-fold increase in Factor XIIIa activity and a 3.2-fold increase in the amount of Factor XIII antigen/mg cell protein. However, there was no increase in the "tissue" transglutaminase activity or antigen levels in cultured monocytes. In addition, we identified a Factor XIII deficient individual who does not express Factor XIII activity or antigen in plasma, platelets, monocytes, lymphocytes or erythrocytes. Intact monocytes from normal donors were able to cross-link fibrin formed in the plasma from the Factor XIII deficient individual. This suggests that transglutaminase activity expressed by peripheral blood monocytes may play a physiologic role in cross-linking fibrin during blood clotting or inflammation. | lld:pubmed |
| pubmed-article:2571199 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2571199 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2571199 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2571199 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2571199 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2571199 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2571199 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2571199 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2571199 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2571199 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2571199 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:2571199 | pubmed:issn | 0049-3848 | lld:pubmed |
| pubmed-article:2571199 | pubmed:author | pubmed-author:WeinbergJ BJB | lld:pubmed |
| pubmed-article:2571199 | pubmed:author | pubmed-author:GreenbergC... | lld:pubmed |
| pubmed-article:2571199 | pubmed:author | pubmed-author:NewcombT FTF | lld:pubmed |
| pubmed-article:2571199 | pubmed:author | pubmed-author:AchyuthanK... | lld:pubmed |
| pubmed-article:2571199 | pubmed:author | pubmed-author:ConklingP RPR | lld:pubmed |
| pubmed-article:2571199 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2571199 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:2571199 | pubmed:volume | 55 | lld:pubmed |
| pubmed-article:2571199 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2571199 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2571199 | pubmed:pagination | 57-68 | lld:pubmed |
| pubmed-article:2571199 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:meshHeading | pubmed-meshheading:2571199-... | lld:pubmed |
| pubmed-article:2571199 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2571199 | pubmed:articleTitle | Human mononuclear phagocyte transglutaminase activity cross-links fibrin. | lld:pubmed |
| pubmed-article:2571199 | pubmed:affiliation | Department of Medicine, Veterans Administration, Durham, North Carolina. | lld:pubmed |
| pubmed-article:2571199 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2571199 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2571199 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:2571199 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2571199 | lld:pubmed |
