Linked Life Data

2569988

Source:http://linkedlifedata.com/resource/pubmed/id/2569988

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1989-9-29
pubmed:abstractText
In chronic experiments on 35 rats, effects on the animals behaviour of intracerebroventricular administration of vasoactive intestinal peptide (VIP) and VIP antiserum were studied under the "open field" conditions before, and on, the 4th and 9th day after local (50%) extirpation of frontal cortex. Sham-operated animals have been used as a control. A considerable regulatory action of VIP on rats' research behaviour was shown (quantity of crossed quadrants, vertical rearing) on the 9th day after the lobectomy. After the operation, the content of noradrenaline (NA), dopamine (DA) and serotonin (5HT) was determined spectrofluorometrically in cortex and subcortical structures. The VIP seemed to exert a regulatory normalizing effect on the neurotransmitters balance in cerebral structures under frontal lobectomy conditions. The most considerable effects were observed in subcortical brain structures and were due to VIP antiserum administration.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0015-329X
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
670-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[The regulatory effect of VIP on exploratory behavior of the rat and on the neuromediator level in the normal brain and in frontal lobectomy].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract