Linked Life Data

2568502

Source:http://linkedlifedata.com/resource/pubmed/id/2568502

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2 Pt 2
pubmed:dateCreated
1989-8-25
pubmed:abstractText
Histomorphometric analysis of semi-thin sections was performed on testicular biopsies of 232 unilaterally cryptorchid testes and 195 of their contralateral descended partners. The results demonstrated a decreased number of germ cells detectable from the first year of life. There was delayed and defective transformation of gonocytes to Ad spermatogonia, which normally is complete at age 6 months, delayed or failed transformation of Ad spermatogonia to primary spermatocytes, which normally commences at age 3 years and decreased numbers of Leydig cells. These abnormalities were present in the unilaterally cryptorchid testes and their contralateral descended partners but they were more severe, of earlier onset and more progressive in the cryptorchid testes. These findings are compatible with the hypothesis that hypogonadotropic hypogonadism is the cause of the increased incidence of infertility seen in unilateral cryptorchidism.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-5347
pubmed:author
pubmed:issnType
Print
pubmed:volume
142
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
546-8; discussion 572
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Postnatal testicular maldevelopment in unilateral cryptorchidism.
pubmed:affiliation
Department of Pathology, University of Medicine and Dentistry of New Jersey, School of Osteopathic Medicine, Camden 08103.
pubmed:publicationType
Journal Article