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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1989-8-1
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pubmed:abstractText |
Stable schizophrenic and schizoaffective outpatients underwent abrupt withdrawal from a fixed dose of neuroleptic. Prolactin concentrations were determined preceding and following drug withdrawal. Basal prolactin concentrations were significantly lower 3, 4, or 5 days following drug withdrawal than on subsequent days. This rebound effect may be related to dopaminergic receptor changes in the tuberoinfundibular system that are induced by chronic neuroleptic administration.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0006-3223
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
131-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2567610-Adult,
pubmed-meshheading:2567610-Antipsychotic Agents,
pubmed-meshheading:2567610-Brain,
pubmed-meshheading:2567610-Female,
pubmed-meshheading:2567610-Fluphenazine,
pubmed-meshheading:2567610-Haloperidol,
pubmed-meshheading:2567610-Humans,
pubmed-meshheading:2567610-Male,
pubmed-meshheading:2567610-Prolactin,
pubmed-meshheading:2567610-Psychotic Disorders,
pubmed-meshheading:2567610-Receptors, Dopamine,
pubmed-meshheading:2567610-Schizophrenia,
pubmed-meshheading:2567610-Substance Withdrawal Syndrome,
pubmed-meshheading:2567610-Trifluoperazine
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pubmed:year |
1989
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pubmed:articleTitle |
Effect of neuroleptic withdrawal on plasma prolactin: a possible marker of receptor adaptation.
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pubmed:affiliation |
Maryland Psychiatric Research Center, Baltimore 21228.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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