pubmed-article:2567431 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2567431 | lifeskim:mentions | umls-concept:C0028778 | lld:lifeskim |
pubmed-article:2567431 | lifeskim:mentions | umls-concept:C0001927 | lld:lifeskim |
pubmed-article:2567431 | lifeskim:mentions | umls-concept:C0700580 | lld:lifeskim |
pubmed-article:2567431 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
pubmed-article:2567431 | pubmed:issue | 8652 | lld:pubmed |
pubmed-article:2567431 | pubmed:dateCreated | 1989-7-21 | lld:pubmed |
pubmed-article:2567431 | pubmed:abstractText | 103 patients with acute airflow obstruction (56 asthma, 47 chronic obstructive pulmonary disease [COPD]) completed a double-blind trial of nebulised bronchodilator treatment in a hospital accident and emergency department. Each patient was randomised to receive either 10 mg of salbutamol nebuliser solution in 2 ml of saline or 10 mg of salbutamol in 2 ml (0.5 mg) of preservative-free ipratropium bromide. Peak flow rate (PFR) was recorded before treatment and 1 hour after beginning nebulised treatment. In 23 asthmatic patients given salbutamol alone PFR rose by a mean 31% 1 hour after treatment whereas in 33 such patients given combined treatment it rose by a mean 77% (95% confidence interval for the difference 8-84%). Patients whose PFR was below 140 l/min at entry gained maximum benefit from the combined treatment. For COPD patients the PFR rise was almost identical for both treatments. In acute asthma the immediate PFR response to a mixture of salbutamol and ipratropium bromide was better than the response to nebulised salbutamol alone. For COPD patients, the two treatments were of equal benefit. | lld:pubmed |
pubmed-article:2567431 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2567431 | pubmed:language | eng | lld:pubmed |
pubmed-article:2567431 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2567431 | pubmed:citationSubset | AIM | lld:pubmed |
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pubmed-article:2567431 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2567431 | pubmed:month | Jun | lld:pubmed |
pubmed-article:2567431 | pubmed:issn | 0140-6736 | lld:pubmed |
pubmed-article:2567431 | pubmed:author | pubmed-author:BernsteinAA | lld:pubmed |
pubmed-article:2567431 | pubmed:author | pubmed-author:TaylorR JRJ | lld:pubmed |
pubmed-article:2567431 | pubmed:author | pubmed-author:ChambersD KDK | lld:pubmed |
pubmed-article:2567431 | pubmed:author | pubmed-author:O'DriscollB... | lld:pubmed |
pubmed-article:2567431 | pubmed:author | pubmed-author:HorsleyM GMG | lld:pubmed |
pubmed-article:2567431 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2567431 | pubmed:day | 24 | lld:pubmed |
pubmed-article:2567431 | pubmed:volume | 1 | lld:pubmed |
pubmed-article:2567431 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2567431 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2567431 | pubmed:pagination | 1418-20 | lld:pubmed |
pubmed-article:2567431 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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pubmed-article:2567431 | pubmed:year | 1989 | lld:pubmed |
pubmed-article:2567431 | pubmed:articleTitle | Nebulised salbutamol with and without ipratropium bromide in acute airflow obstruction. | lld:pubmed |
pubmed-article:2567431 | pubmed:affiliation | Hope Hospital, Salford. | lld:pubmed |
pubmed-article:2567431 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2567431 | pubmed:publicationType | Clinical Trial | lld:pubmed |
pubmed-article:2567431 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:2567431 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
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