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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
6222
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pubmed:dateCreated |
1989-6-27
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pubmed:abstractText |
We show that cyclin plays a pivotal role in the control of mitosis. A proteolysis-resistant mutant of cyclin prevents the inactivation of maturation promoting factor and the exit from mitosis both in vivo and in vitro. We have used a fractionated extract to study the activation of MPF by added cyclin protein.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
May
|
|
pubmed:issn |
0028-0836
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
25
|
|
pubmed:volume |
339
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
280-6
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|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:2566918-Animals,
pubmed-meshheading:2566918-Cell Cycle,
pubmed-meshheading:2566918-Embryo, Nonmammalian,
pubmed-meshheading:2566918-Female,
pubmed-meshheading:2566918-Growth Substances,
pubmed-meshheading:2566918-Kinetics,
pubmed-meshheading:2566918-Maturation-Promoting Factor,
pubmed-meshheading:2566918-Meiosis,
pubmed-meshheading:2566918-Mitosis,
pubmed-meshheading:2566918-Nuclear Proteins,
pubmed-meshheading:2566918-Ovum,
pubmed-meshheading:2566918-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:2566918-Xenopus
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|
pubmed:year |
1989
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|
pubmed:articleTitle |
The role of cyclin synthesis and degradation in the control of maturation promoting factor activity.
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pubmed:affiliation |
Department of Biochemistry and Biophysics, School of Medicine, University of California, San Francisco 94143-0448.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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