rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8650
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pubmed:dateCreated |
1989-7-6
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pubmed:abstractText |
The rates of propionate production and aminoacid catabolism in 5 children with methylmalonic acidaemia were measured by use of stable isotope techniques. Total propionate production was 55-186 mumol/kg per h, to which the maximum contribution of protein catabolism was 10-35 mumol/kg per h (5-40%). These findings indicate important sources of propionate other than protein catabolism, which may account for the limited efficacy of dietary protein restriction in treatment of methylmalonic acidaemia.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acyl Coenzyme A,
http://linkedlifedata.com/resource/pubmed/chemical/Amino Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Isoleucine,
http://linkedlifedata.com/resource/pubmed/chemical/Leucine,
http://linkedlifedata.com/resource/pubmed/chemical/Malonates,
http://linkedlifedata.com/resource/pubmed/chemical/Methionine,
http://linkedlifedata.com/resource/pubmed/chemical/Methylmalonic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Phenylalanine,
http://linkedlifedata.com/resource/pubmed/chemical/Threonine,
http://linkedlifedata.com/resource/pubmed/chemical/Valine,
http://linkedlifedata.com/resource/pubmed/chemical/propionyl-coenzyme A
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0140-6736
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1298-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2566828-Acyl Coenzyme A,
pubmed-meshheading:2566828-Adult,
pubmed-meshheading:2566828-Amino Acid Metabolism, Inborn Errors,
pubmed-meshheading:2566828-Amino Acids,
pubmed-meshheading:2566828-Child,
pubmed-meshheading:2566828-Humans,
pubmed-meshheading:2566828-Isoleucine,
pubmed-meshheading:2566828-Kinetics,
pubmed-meshheading:2566828-Leucine,
pubmed-meshheading:2566828-Malonates,
pubmed-meshheading:2566828-Methionine,
pubmed-meshheading:2566828-Methylmalonic Acid,
pubmed-meshheading:2566828-Phenylalanine,
pubmed-meshheading:2566828-Threonine,
pubmed-meshheading:2566828-Time Factors,
pubmed-meshheading:2566828-Valine
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pubmed:year |
1989
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pubmed:articleTitle |
Contribution of aminoacid catabolism to propionate production in methylmalonic acidaemia.
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pubmed:affiliation |
Department of Child Health, Institute of Child Health, London.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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