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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1991-12-9
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pubmed:abstractText |
The hypotensive effect of enalapril, a converting enzyme inhibitor, given as a single agent once daily, was evaluated prospectively over a 16 week period in 20 subjects. One patient abandoned therapy and 2 were withdrawn (increased creatinine levels in one and the need for associated therapy in the other). Side effects developed in 3 patients: creatinine elevation, skin rush and a "salty taste", respectively. A significant decrease in blood pressure (p less than 0.01) attaining normal levels in 6 out of 17 patients was observed. Normal blood pressure levels were not reached in severe hypertension; the association of hydrochlorothyazide was effective in 5 of 11 such subjects. Thus, enalapril may be safely used as a first stage single therapy in mild or moderate hypertension.
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pubmed:language |
spa
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0034-9887
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
667-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2562413-Adult,
pubmed-meshheading:2562413-Aged,
pubmed-meshheading:2562413-Blood Pressure,
pubmed-meshheading:2562413-Drug Therapy, Combination,
pubmed-meshheading:2562413-Enalapril,
pubmed-meshheading:2562413-Female,
pubmed-meshheading:2562413-Humans,
pubmed-meshheading:2562413-Hydrochlorothiazide,
pubmed-meshheading:2562413-Hypertension,
pubmed-meshheading:2562413-Male,
pubmed-meshheading:2562413-Middle Aged
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pubmed:year |
1989
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pubmed:articleTitle |
[Enalapril in essential arterial hypertension].
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pubmed:publicationType |
Journal Article,
English Abstract
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