Linked Life Data

2561877

Source:http://linkedlifedata.com/resource/pubmed/id/2561877

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-9-27
pubmed:abstractText
Image localized 31P magnetic resonance (MR) spectroscopy of the liver was performed in twelve normal volunteers and seven patients with hepatic tumours. The tumours which were clearly imaged by proton MR could also be distinguished from normal tissue because of spectral differences. The malignant tumours had significantly elevated phosphomonoester/inorganic phosphate and phosphomonoester/beta-adenosine triphosphate ratios, probably due to elevated tumour concentrations of phosphocholine and phosphoethanolamine, which are intermediates in the synthesis of membrane phospholipids. The pH values of the malignant tumours were elevated compared to normal hepatic parenchyma. Liver spectra in two patients with the commonest benign hepatic neoplasm, cavernous haemangioma, differed from both normal tissue and the malignant tumours in having a very low signal/noise ratio but apparently normal relative levels of phosphomonoester.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0952-3480
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
184-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Image localized 31P magnetic resonance spectroscopy of the human liver.
pubmed:affiliation
Magnetic Resonance Research Centre, University of Liverpool, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't