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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1990-4-6
|
pubmed:abstractText |
In Papua New Guinea the slow acetylator phenotype is unusual and peripheral neuropathy during isoniazid therapy is uncommon. Acetylator status and other factors influencing isoniazid-induced peripheral neuropathy are discussed, and statistics from Papua New Guinea are presented. The relevance of acetylator phenotype to other side-effects of isoniazid is less well defined. Prophylactic pyridoxine supplementation during short-course chemotherapy for tuberculosis is not generally necessary in the daily 'A' regimen, but should be maintained in the twice-weekly (high-dose isoniazid) 'B' regimen for adults and children over 20 kg.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0031-1480
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
259-62
|
pubmed:dateRevised |
2005-11-16
|
pubmed:meshHeading |
pubmed-meshheading:2560598-Acetylation,
pubmed-meshheading:2560598-Drug Administration Schedule,
pubmed-meshheading:2560598-Humans,
pubmed-meshheading:2560598-Isoniazid,
pubmed-meshheading:2560598-Papua New Guinea,
pubmed-meshheading:2560598-Peripheral Nervous System Diseases,
pubmed-meshheading:2560598-Phenotype,
pubmed-meshheading:2560598-Pyridoxine,
pubmed-meshheading:2560598-Time Factors,
pubmed-meshheading:2560598-Tuberculosis
|
pubmed:year |
1989
|
pubmed:articleTitle |
Acetylator phenotype and short-course chemotherapy for tuberculosis in Papua New Guinea.
|
pubmed:publicationType |
Journal Article,
Review
|