| pubmed-article:2556385 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2556385 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:2556385 | lifeskim:mentions | umls-concept:C0033634 | lld:lifeskim |
| pubmed-article:2556385 | lifeskim:mentions | umls-concept:C0039654 | lld:lifeskim |
| pubmed-article:2556385 | lifeskim:mentions | umls-concept:C0600508 | lld:lifeskim |
| pubmed-article:2556385 | lifeskim:mentions | umls-concept:C0969709 | lld:lifeskim |
| pubmed-article:2556385 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:2556385 | lifeskim:mentions | umls-concept:C0332291 | lld:lifeskim |
| pubmed-article:2556385 | pubmed:issue | 35 | lld:pubmed |
| pubmed-article:2556385 | pubmed:dateCreated | 1990-1-19 | lld:pubmed |
| pubmed-article:2556385 | pubmed:abstractText | Transfection of the cDNA encoding the activated c-raf-1 protein or addition of 12-O-tetradecanoylphorbol-13-acetate (TPA) or dibutyryl cAMP to NIH/3T3 cells activated the c-fos gene enhancer linked to the chloramphenicol acetyltransferase or luciferase reporter gene. Prolonged treatment of NIH/3T3 cells with phorbol 12,13-dibutyrate caused down-regulation of protein kinase C. In these cells, addition of TPA did not stimulate the c-fos gene enhancer any more, but transfection of the c-raf-1 cDNA or addition of dibutyryl cAMP still stimulated the c-fos gene enhancer to the same extent as those induced in the control cells. Transfection of the c-raf-1 cDNA or addition of TPA to NIH/3T3 cells stimulated the serum response element and TPA response element but not the cAMP response element. In contrast, addition of dibutyryl cAMP to NIH/3T3 cells stimulated the cAMP response element but not the serum response element or TPA response element. These results indicate that the activated c-raf-1 protein stimulates the serum response element and TPA response element in a manner independent of protein kinase C and cAMP-dependent protein kinase. Since the c-fos gene enhancer has been shown to contain the serum response element and cAMP response element, it is most likely that the c-raf-1 protein is involved in the regulation of c-fos gene expression through the serum response element. | lld:pubmed |
| pubmed-article:2556385 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2556385 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2556385 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2556385 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:2556385 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:2556385 | pubmed:author | pubmed-author:HoriYY | lld:pubmed |
| pubmed-article:2556385 | pubmed:author | pubmed-author:YamamotoTT | lld:pubmed |
| pubmed-article:2556385 | pubmed:author | pubmed-author:ToyoshimaKK | lld:pubmed |
| pubmed-article:2556385 | pubmed:author | pubmed-author:TakaiYY | lld:pubmed |
| pubmed-article:2556385 | pubmed:author | pubmed-author:FukumotoYY | lld:pubmed |
| pubmed-article:2556385 | pubmed:author | pubmed-author:OkuNN | lld:pubmed |
| pubmed-article:2556385 | pubmed:author | pubmed-author:KaibuchiKK | lld:pubmed |
| pubmed-article:2556385 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2556385 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:2556385 | pubmed:volume | 264 | lld:pubmed |
| pubmed-article:2556385 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2556385 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2556385 | pubmed:pagination | 20855-8 | lld:pubmed |
| pubmed-article:2556385 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:meshHeading | pubmed-meshheading:2556385-... | lld:pubmed |
| pubmed-article:2556385 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2556385 | pubmed:articleTitle | Activation of the serum response element and 12-O-tetradecanoylphorbol-13-acetate response element by the activated c-raf-1 protein in a manner independent of protein kinase C. | lld:pubmed |
| pubmed-article:2556385 | pubmed:affiliation | Department of Biochemistry, Kobe University School of Medicine, Japan. | lld:pubmed |
| pubmed-article:2556385 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2556385 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2556385 | lld:pubmed |
