| pubmed-article:2555532 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2555532 | lifeskim:mentions | umls-concept:C0026969 | lld:lifeskim |
| pubmed-article:2555532 | lifeskim:mentions | umls-concept:C1882598 | lld:lifeskim |
| pubmed-article:2555532 | lifeskim:mentions | umls-concept:C0017889 | lld:lifeskim |
| pubmed-article:2555532 | lifeskim:mentions | umls-concept:C0031716 | lld:lifeskim |
| pubmed-article:2555532 | lifeskim:mentions | umls-concept:C1753334 | lld:lifeskim |
| pubmed-article:2555532 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2555532 | pubmed:dateCreated | 1989-12-28 | lld:pubmed |
| pubmed-article:2555532 | pubmed:abstractText | Myelin isolated from rat brain possessed the ability to release phosphorylcholine from glycerophosphorylcholine, and this activity was enriched 3.2-fold over that of the original homogenate. This glycerophosphorylcholine phosphocholine phosphodiesterase activity had a pH optimum at 9.5, had a Km of 0.2 mM, and a Vmax of 150 nmoles/mg protein/hr. The enzyme had a specific requirement for Zn+2 with an optimum concentration at 0.25 mM. Maximum enzyme activity was at 50 degrees C and an Arrhenius plot showed a breakpoint at 40 degrees. p-Nitrophenylphosphorylcholine was also hydrolyzed by purified myelin and was a competitive inhibitor of glycerophosphorylcholine phosphocholine phosphodiesterase activity with a Ki of 0.075 mM. Glycerolphosphorylethanolamine was hydrolyzed only 5% compared with GPC, but it was not an inhibitor. | lld:pubmed |
| pubmed-article:2555532 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2555532 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2555532 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2555532 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2555532 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2555532 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2555532 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2555532 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2555532 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2555532 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2555532 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:2555532 | pubmed:issn | 0360-4012 | lld:pubmed |
| pubmed-article:2555532 | pubmed:author | pubmed-author:KanferJ NJN | lld:pubmed |
| pubmed-article:2555532 | pubmed:author | pubmed-author:McCartneyD... | lld:pubmed |
| pubmed-article:2555532 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2555532 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:2555532 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2555532 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2555532 | pubmed:pagination | 231-40 | lld:pubmed |
| pubmed-article:2555532 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:meshHeading | pubmed-meshheading:2555532-... | lld:pubmed |
| pubmed-article:2555532 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2555532 | pubmed:articleTitle | Glycerophosphorylcholine phosphocholine phosphodiesterase activity of rat brain myelin. | lld:pubmed |
| pubmed-article:2555532 | pubmed:affiliation | Department of Biochemistry, University of Manitoba, Winnipeg, Canada. | lld:pubmed |
| pubmed-article:2555532 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2555532 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2555532 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2555532 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2555532 | lld:pubmed |
