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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1989-11-30
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pubmed:abstractText |
Hypothalamic concentrations of epinephrine and norepinephrine were determined in rats following 6-hydroxydopamine lesions of the locus coeruleus and subcoeruleus system and following sham-operation. These concentrations were correlated with pituitary ACTH content. While the lesion procedure did not have a major effect on hypothalamic monoamine levels, we were able to demonstrate a strong negative correlation between hypothalamic epinephrine and pituitary ACTH content independent of the experimental condition. Only a weak negative correlation was observed for hypothalamic norepinephrine and pituitary ACTH. Our recent and previous data suggest a tonic and phasic inhibition of ACTH release by hypothalamic monoamines.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-9130
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
189
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
289-93
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2554439-Adrenocorticotropic Hormone,
pubmed-meshheading:2554439-Animals,
pubmed-meshheading:2554439-Epinephrine,
pubmed-meshheading:2554439-Hypothalamus,
pubmed-meshheading:2554439-Male,
pubmed-meshheading:2554439-Norepinephrine,
pubmed-meshheading:2554439-Pituitary Gland, Anterior,
pubmed-meshheading:2554439-Rats,
pubmed-meshheading:2554439-Rats, Inbred Strains,
pubmed-meshheading:2554439-Tyrosine
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pubmed:year |
1989
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pubmed:articleTitle |
Relationship between pituitary ACTH content and hypothalamic catecholamines in the rat.
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pubmed:affiliation |
Third Medical University Hospital, Dept. of Internal Medicine, Endocrinology and Metabolism, Mainz, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study
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