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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12-13
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pubmed:dateCreated |
1989-12-14
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pubmed:abstractText |
An effect of enalapril maleate on the activity of renin-angiotensin-aldosterone system and sympathetic reactivity, erythrocyte prostaglandin and sodium levels as well as blood beta-endorphin was investigated in 28 patients with the essential arterial blood hypertension. It was found that enalapril maleate significantly increased plasma renin activity, decreased plasma norepinephrine and its 24-hour excretion, and decreased erythrocyte beta-endorphin and sodium levels. Blood epinephrine and aldosterone levels and their daily excretion remained unchanged similarly to prostaglandins. The above results suggest that a decrease in sympathetic system activity and intracellular sodium concentration may play a role in the hypotensive action of enalapril maleate related to the inhibition of angiotensin II formation.
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pubmed:language |
pol
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Catecholamines,
http://linkedlifedata.com/resource/pubmed/chemical/Enalapril,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandins,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Endorphin
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pubmed:status |
MEDLINE
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pubmed:issn |
0032-3756
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
297-300
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pubmed:dateRevised |
2008-6-20
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pubmed:meshHeading |
pubmed-meshheading:2554261-Adult,
pubmed-meshheading:2554261-Catecholamines,
pubmed-meshheading:2554261-Enalapril,
pubmed-meshheading:2554261-Erythrocytes,
pubmed-meshheading:2554261-Female,
pubmed-meshheading:2554261-Humans,
pubmed-meshheading:2554261-Hypertension,
pubmed-meshheading:2554261-Male,
pubmed-meshheading:2554261-Middle Aged,
pubmed-meshheading:2554261-Prostaglandins,
pubmed-meshheading:2554261-Renin-Angiotensin System,
pubmed-meshheading:2554261-Sodium,
pubmed-meshheading:2554261-beta-Endorphin
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pubmed:articleTitle |
[Effect of treatment with enalapril maleate on the levels of circulating catecholamines, beta endorphins, prostaglandins, and concentration of sodium in erythrocytes in patients with essential hypertension].
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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