Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
|
pubmed:dateCreated |
1989-12-21
|
pubmed:abstractText |
The distribution of calcitonin gene-related peptide (CGRP) and its binding sites in the bulbocavernosus, a striated muscle, are reported. We used immunohistochemistry and [125I]CGRP autoradiography. The pattern of [125I]CGRP binding was restricted to a discrete band that coincides with the distribution of end-plates in this muscle as determined by CGRP immunohistochemistry and acetylcholinesterase staining. CGRP has been shown to increase the level of acetylcholine receptor (AChR) alpha-subunit mRNA. The role of CGRP as the endogenous factor by which motoneurons regulate the expression of junctional AChR is discussed.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0006-8993
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
4
|
pubmed:volume |
496
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
180-6
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:2553200-Animals,
pubmed-meshheading:2553200-Calcitonin Gene-Related Peptide,
pubmed-meshheading:2553200-Immunohistochemistry,
pubmed-meshheading:2553200-Male,
pubmed-meshheading:2553200-Motor Endplate,
pubmed-meshheading:2553200-Motor Neurons,
pubmed-meshheading:2553200-Muscles,
pubmed-meshheading:2553200-Neuromuscular Junction,
pubmed-meshheading:2553200-Rats,
pubmed-meshheading:2553200-Receptors, Cell Surface
|
pubmed:year |
1989
|
pubmed:articleTitle |
Localization of calcitonin gene-related peptide and its receptors in a striated muscle.
|
pubmed:affiliation |
Department of Anatomy, UCLA School of Medicine 90024.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|