Linked Life Data

2551991

Source:http://linkedlifedata.com/resource/pubmed/id/2551991

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1989-11-1
pubmed:abstractText
Zinc concentrations and Cu, Zn superoxide dismutase activity in erythrocytes were investigated in 138 healthy children and in 35 children with cancer. The mean zinc concentration in the erythrocytes of healthy children was found to be age-dependent. In the youngest group (children up to 1 year of age) the zinc concentration in erythrocytes is 18.8 +/- 3.4 micrograms/g Hb (5.89 +/- 1.23 mg/l packed cells), which is significantly lower than in other age groups. A strong logarithmic correlation (r = 0.327, p less than 0.0001 and r = 0.436, p less than 0.00001) was found between age and zinc concentration in erythrocytes, expressed as microgram/g Hb and as mg/l packed red cells, respectively. Cancer children were divided into two groups (neuro- and nephroblastoma). In the group of children with neuroblastoma no statistical differences in zinc concentration or enzyme activity were observed. In the patients with nephroblastoma, significantly higher zinc concentrations (p less than 0.05) were observed in erythrocytes. The changes of zinc concentration are accompanied by significant (p less than 0.02) decreases of enzyme activity. In this group of cancer children, statistically significant differences were observed in the zinc concentrations in erythrocytes (microgram/g Hb) between the second and the third stages of the disease. No correlation was observed between the concentration of zinc and enzyme activity in healthy children or in cancer children.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0340-076X
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
413-8
pubmed:dateRevised
2007-7-24
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Concentration of zinc and zinc-copper superoxide dismutase activity in red blood cells in normals and children with cancer.
pubmed:affiliation
Department of Biochemistry, Institute of Basic Sciences WAM, Lód?, Poland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't