Linked Life Data

2550639

Source:http://linkedlifedata.com/resource/pubmed/id/2550639

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-10-20
pubmed:abstractText
The safety and efficacy of once-daily lisinopril was assessed in an 8-week open-label study of 24 elderly patients with mild to moderate hypertension. Following withdrawal of all previous antihypertensive treatment, including diuretics, lisinopril treatment was started at a dose of 5 mg, increasing to a maximum of 40 mg once daily as required. Treatment provided effective 24-h BP control in all patients, most of whom required a daily dose of 20-40 mg, and cardiothoracic index decreased significantly, indicating a favourable effect on left ventricular volumes. There were no significant ECG alterations and no major side effects occurred. It is concluded that lisinopril 5 mg is a safe starting dose for elderly patients who are not on diuretics, and that once-daily lisinopril monotherapy reduces BP safety without affecting heart rate.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0950-9240
pubmed:author
pubmed:issnType
Print
pubmed:volume
3 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Safety and efficacy of lisinopril in elderly patients with mild to moderate hypertension.
pubmed:affiliation
Bijloke Ziekenhuis, Gent, Belgium.
pubmed:publicationType
Journal Article, Comparative Study