rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1-3
|
pubmed:dateCreated |
1989-9-15
|
pubmed:abstractText |
Using an antiserum (AS) raised against rat cerebral acetylcholinesterase (AChE), we revealed a neuron population in lateral and dorsal areas of the posterior rat hypothalamus. These neurons were previously described using antibodies to human growth hormone-releasing factor(1-37) (GRF-37), alpha-melanotropin (alpha-MSH) and melanin-concentrating hormone (MCH). Different intracytoplasmic distributions of the immunodeposits were observed depending on the used serum. Ultrastructural investigations demonstrated that AChE-AS labeled rough endoplasmic reticulum and nuclear envelope in control rats. MCH-AS stained Golgi apparatus in control animals and secretory granules in colchicine-injected rats. GRF-37-AS always revealed secretory granules, and alpha-MSH-AS gave the same staining only after colchicine injection.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0304-3940
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
22
|
pubmed:volume |
100
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
23-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2548128-Acetylcholinesterase,
pubmed-meshheading:2548128-Animals,
pubmed-meshheading:2548128-Endoplasmic Reticulum,
pubmed-meshheading:2548128-Golgi Apparatus,
pubmed-meshheading:2548128-Growth Hormone-Releasing Hormone,
pubmed-meshheading:2548128-Hypothalamic Hormones,
pubmed-meshheading:2548128-Hypothalamus,
pubmed-meshheading:2548128-Immunohistochemistry,
pubmed-meshheading:2548128-Melanins,
pubmed-meshheading:2548128-Microscopy, Electron,
pubmed-meshheading:2548128-Pituitary Hormones,
pubmed-meshheading:2548128-Rats,
pubmed-meshheading:2548128-Rats, Inbred Strains,
pubmed-meshheading:2548128-alpha-MSH
|
pubmed:year |
1989
|
pubmed:articleTitle |
Coexistence of acetylcholinesterase-, human growth hormone-releasing factor(1-37)-, alpha-melanotropin- and melanin-concentrating hormone-like immunoreactivities in neurons of the rat hypothalamus: a light and electron microscope study.
|
pubmed:affiliation |
CNRS URA 561, Laboratoire d'Histologie Embryologie Cytogénétique, Faculté de Médecine, Besançon, France.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|