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pubmed-article:2547854pubmed:abstractTextThirty plantar warts were analyzed for the presence of HPV-1 type-specific and PV genus-specific capsid antigens by immunofluorescence (IF) using monoclonal and polyclonal antibodies and type-specific HPV-1 DNA employing in situ hybridization methods. Fifteen of 30 plantar warts were positive by IF for PV genus-specific structural viral antigens. Thirteen of the 15 productively infected plantar warts expressed intranuclear HPV-1 type-specific capsid antigens and viral DNA, which were detected in the same distribution in each individual wart. The 2 productively infected plantar warts that did not react with HPV-1 type-specific MoAbs did not react with HPV-1 type-specific DNA by in situ hybridization. Thus, serotyping of HPV-1 capsid antigens by monoclonal antibodies is concordant with genotyping of HPV-1 viral DNA by in situ hybridization in productively infected plantar warts.lld:pubmed
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pubmed-article:2547854pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:2547854pubmed:articleTitleComparison of human papillomavirus type 1 serotyping by monoclonal antibodies with genotyping by in situ hybridization of plantar warts.lld:pubmed
pubmed-article:2547854pubmed:affiliationDepartment of Pathology, Georgetown University School of Medicine, Washington DC 20007.lld:pubmed
pubmed-article:2547854pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2547854pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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