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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1989-9-19
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pubmed:abstractText |
Thirty plantar warts were analyzed for the presence of HPV-1 type-specific and PV genus-specific capsid antigens by immunofluorescence (IF) using monoclonal and polyclonal antibodies and type-specific HPV-1 DNA employing in situ hybridization methods. Fifteen of 30 plantar warts were positive by IF for PV genus-specific structural viral antigens. Thirteen of the 15 productively infected plantar warts expressed intranuclear HPV-1 type-specific capsid antigens and viral DNA, which were detected in the same distribution in each individual wart. The 2 productively infected plantar warts that did not react with HPV-1 type-specific MoAbs did not react with HPV-1 type-specific DNA by in situ hybridization. Thus, serotyping of HPV-1 capsid antigens by monoclonal antibodies is concordant with genotyping of HPV-1 viral DNA by in situ hybridization in productively infected plantar warts.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0303-6987
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
54-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2547854-Antibodies, Monoclonal,
pubmed-meshheading:2547854-DNA, Viral,
pubmed-meshheading:2547854-Fluorescent Antibody Technique,
pubmed-meshheading:2547854-Foot Diseases,
pubmed-meshheading:2547854-Genotype,
pubmed-meshheading:2547854-Humans,
pubmed-meshheading:2547854-Nucleic Acid Hybridization,
pubmed-meshheading:2547854-Papillomaviridae,
pubmed-meshheading:2547854-Serotyping,
pubmed-meshheading:2547854-Warts
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pubmed:year |
1989
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pubmed:articleTitle |
Comparison of human papillomavirus type 1 serotyping by monoclonal antibodies with genotyping by in situ hybridization of plantar warts.
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pubmed:affiliation |
Department of Pathology, Georgetown University School of Medicine, Washington DC 20007.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|