Linked Life Data

2546663

Source:http://linkedlifedata.com/resource/pubmed/id/2546663

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-9-1
pubmed:abstractText
Two bronchiolo-alveolar carcinomas of Clara cell type have been studied by thin section and freeze-fracture techniques. Thin sections of the tumour cells showed junctional complexes (tight junctions and intermediate junctions) at the luminal aspect of the lateral cell membranes and desmosomes below them. Freeze-fracture replicas showed well-developed tight junctions with strands arranged in parallel or polygonal patterns. The junctions were continuous 'zonula occludens' type, usually three or more strands deep, with focal proliferation in some areas. The granules in the tumour cells tended to be larger than those of normal human Clara cells, although they were morphologically similar. There was no evidence of secretion of granules from the tumour cells. The relationships between tumour differentiation and growth pattern, and junctional development are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1122-9497
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
239-47
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Freeze-fracture study of the intercellular junctions in bronchiolo-alveolar carcinoma (Clara cell type).
pubmed:affiliation
Division of Tissue Pathology, Institute of Medical and Veterinary Science, Adelaide, Australia.
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't