Linked Life Data

2545373

Source:http://linkedlifedata.com/resource/pubmed/id/2545373

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-8-15
pubmed:abstractText
Neural development proceeds in an ordered fashion in which a variety of genetic and epigenetic factors exert an influence at well defined times. Using a cloned chicken genomic fragment for the nerve growth factor (NGF) receptor, we have detected strong expression in chicken brain at early stages of embryonic development. Expression of the receptor gene was greatly diminished at birth. This pattern of NGF receptor mRNA level was observed in all cranial regions and was further correlated with the appearance and disappearance of cell surface receptors. The transient developmental expression of NGF receptors in chick brain and the requirement for receptors to mediate NGF's effects suggests that NGF may possess a broader range of actions during development of the nervous system.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0165-3806
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
187-96
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Developmental expression of the chicken nerve growth factor receptor gene during brain morphogenesis.
pubmed:affiliation
Department of Cell Biology and Anatomy, Cornell University Medical College, New York, NY 10021.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't