Linked Life Data

2542815

Source:http://linkedlifedata.com/resource/pubmed/id/2542815

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-7-10
pubmed:abstractText
The effect of LTC4, a synthetic leukotriene, and of BW 755C, a blocker of its biosynthesis on the functioning of Ca-channels in the membrane of snail neurons and on the contractile activity of rat uterus muscles in late terms of pregnancy was studied by means of intracellular dialysis and spontaneous contractility recording techniques. It was found that the 10(-7) mol/l of LTC4 stimulated the contractile function of the rat uterus and activated effectively the Ca-conductance in the somatic membrane of the nervous cell. The action of BW 755C was similar to that of leukotriene on Ca-conductance; in addition BW 755C produced transient activation of contractions of the rat uterus followed by a complete suppression of smooth muscle contractions. Possible mechanisms of the effects described were discussed.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0028-2561
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
24-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Features of the effect of leukotriene LTC4 and the blocker of its biosynthesis BW755C on the contractile capability of smooth muscles and the functioning of potential-dependent calcium channels of the nerve cell].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract