Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-6-20
pubmed:abstractText
Single spinal dorsal horn neuronal responses to noxious skin heating or innocuous skin brushing were recorded in pentobarbital anesthetized rats. The heat-evoked activity was selectively abolished by blockade of GABAA receptors in the midbrain periaqueductal grey (PAG) by microinjections of 40 or 400 pmol bicuculline. It is concluded that antinociceptive output neurons in the PAG that trigger descending inhibition are maximally active when released from tonic GABAergic inhibition.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
24
pubmed:volume
160
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Blockade of GABAA receptors in the midbrain periaqueductal gray abolishes nociceptive spinal dorsal horn neuronal activity.
pubmed:affiliation
Universität Heidelberg II, Physiologisches Institut, F.R.G.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't