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pubmed-article:2538205pubmed:abstractTextThe hypothesis according to which botulinum A toxin blocks acetylcholine release from motor endings by stimulating intracellular Ca2+ disposal systems was tested by recording presynaptic membrane currents from poisoned muscles. Calcium and calcium-activated potassium currents displayed amplitudes, time courses and stimulation frequency-dependent inactivation similar to those observed in unpoisoned preparations. This indicates that poisoned endings are no more efficient than normal ones in dealing with Ca2+ overloads.lld:pubmed
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pubmed-article:2538205pubmed:articleTitleIs the internal calcium regulation altered in type A botulinum toxin-poisoned motor endings?lld:pubmed
pubmed-article:2538205pubmed:affiliationLaboratoire de Neurobiologie Cellulaire et Moléculaire, C.N.R.S., Gif sur Yvette, France.lld:pubmed
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