Linked Life Data

2537751

Source:http://linkedlifedata.com/resource/pubmed/id/2537751

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-4-7
pubmed:abstractText
The effect of the mitogen bombesin on pHi in cells of the chick otic vesicle was studied using dual wavelength micro-spectrofluorimetric techniques. The results show that the bombesin did not produce an immediate alkalinization in quiescent otic vesicle cells nor a long-term change in pHi in vesicles reactivated to grow in culture. The recovery of pHi from an acid load, caused by an NH4 pulse, involved both Na+/H+ exchange and Na+:HCO3 influx mechanisms, neither of which was influenced by bombesin. These observations do not fit with a general model whereby pHi is a universal signal for DNA replication and cell proliferation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
243
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-20
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Growth stimulation by bombesin does not involve activation of Na+/H+ exchange in chick embryo otic vesicles in vitro.
pubmed:affiliation
Department of Physiological Sciences, Medical School, The University, Newcastle upon Tyne, England.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't