Linked Life Data

2536530

Source:http://linkedlifedata.com/resource/pubmed/id/2536530

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-2-27
pubmed:abstractText
Colony-stimulating factors are growth factors responsible for the proliferation and the maturation of bone marrow stem cells to fully differentiated granulocytes and monocytes. In addition to their effects on hematopoiesis, some colony-stimulating factors prime mature cells for enhanced chemotaxis, phagocytosis, and killing in response to physiologic stimuli. The action of colony-stimulating factors is mediated by growth factor receptors on precursor and mature effector cells. The results of studies of granulocyte-macrophage colony-stimulating factors in patients with the acquired immunodeficiency syndrome (AIDS) suggest a possible therapeutic role for colony-stimulating factors in augmenting mechanism of host defense.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0003-4819
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
110
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
297-303
pubmed:dateRevised
2010-4-12
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Colony-stimulating factors and host defense.
pubmed:affiliation
Department of Medicine, UCLA School of Medicine.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Review