Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-10-9
pubmed:abstractText
Neutral glycolipids and gangliosides from seven human urothelial cell lines, differing in grades of transformation (TGr), were characterized by fast atom bombardment mass spectrometry, exoglycosidase treatment and an immunostaining procedure. The major neutral glycolipids identified in all cell lines studied included CMH, CDH, CTH, globoside and paragloboside, the gangliosides were GM3, GM2, sialosylparagloboside and GD1a. The following observations were made: 1. GM2 was the major ganglioside in the TGrII cell lines (non-tumorigenic, non-invasive), but a minor component in the TGrIII cell lines (tumorigenic, invasive). 2. All components showed C16:0 and C24:0 as major fatty acids, but in the TGrIII cell lines the fatty acid composition of CMH and some of the gangliosides were more complex showing unsaturated and hydroxy-fatty acids as well.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0282-0080
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
303-18
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:2535491-Antibodies, Monoclonal, pubmed-meshheading:2535491-Carbohydrate Conformation, pubmed-meshheading:2535491-Carbohydrate Sequence, pubmed-meshheading:2535491-Carbon Radioisotopes, pubmed-meshheading:2535491-Carcinoma, Transitional Cell, pubmed-meshheading:2535491-Cell Line, pubmed-meshheading:2535491-Cell Transformation, Neoplastic, pubmed-meshheading:2535491-Epithelium, pubmed-meshheading:2535491-Galactose, pubmed-meshheading:2535491-Gangliosides, pubmed-meshheading:2535491-Glycoside Hydrolases, pubmed-meshheading:2535491-Glycosphingolipids, pubmed-meshheading:2535491-Humans, pubmed-meshheading:2535491-Immunoblotting, pubmed-meshheading:2535491-Molecular Sequence Data, pubmed-meshheading:2535491-Radioisotope Dilution Technique, pubmed-meshheading:2535491-Spectrometry, Mass, Fast Atom Bombardment, pubmed-meshheading:2535491-Urinary Bladder, pubmed-meshheading:2535491-Urinary Bladder Neoplasms
pubmed:year
1989
pubmed:articleTitle
Glycosphingolipids of human urothelial cell lines with different grades of transformation.
pubmed:affiliation
Department of Immunochemistry, Polish Academy of Sciences, Wroclaw.
pubmed:publicationType
Journal Article, Comparative Study