Linked Life Data

2534319

Source:http://linkedlifedata.com/resource/pubmed/id/2534319

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-5-8
pubmed:abstractText
To determine the effect of age on the modification of brain lipids and functions by fish oil and lard diets, the polyunsaturated fatty acids, phospholipid states and enzyme activities of intracellular organelles in young and aged rats fed these diets were analyzed. The concentration of arachidonic acid (20:4) and docosahexaenoic acid (22:6) tended to decrease with increasing age. The UV absorption of phosphatidylethanolamine (PE) and phosphatidylcholine (PC) also decreased. An increasing effect of the sardine oil diet on brain 22:6 concentration in aged rats was slightly greater than that in young rats. However, the modification of 20:4 concentration in aged rats was similar to that in young rats. Significant increases in the UV absorption of PE and PC of aged rats fed the fish oil diet were observed. The lactate dehydrogenase (LDH) activities of aged rats fed the sardine oil diet increased significantly, whereas the activities of aged rats fed the lard diet decreased. These results suggest that fish oil may be able to regulate the brain lipid composition and LDH activity in aged rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0047-6374
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-25
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Effect of age on the modification of brain polyunsaturated fatty acids and enzyme activities by fish oil diet in rats.
pubmed:affiliation
National Food Research Institute, Ibaraki, Japan.
pubmed:publicationType
Journal Article