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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1990-3-8
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pubmed:abstractText |
In iron-deficient conditions of growth Pseudomonas cepacia ATCC 25416 excreted both pyochelin and a low-molecular-mass compound which strongly chelated iron(III), and facilitated iron translocation as demonstrated by growth and uptake experiments. The name cepabactin is proposed for this new siderophore. Comparisons of UV-visible spectra and chromatographic behaviour, together with 1H-NMR spectra, led to the conclusion that cepabactin is 1-hydroxy-5-methoxy-6-methyl-2(1H)-pyridinone, a compound which can be considered as a cyclic hydroxamate, but also as a heterocyclic analogue of catechol. This pyridinone has already been described by other workers as an antibiotic produced by Pseudomonas alcaligenes, and by a soil isolate closely related to Pseudomonas cepacia. Thus, cepabactin appears to act as a siderophore for more than one species of non-fluorescent pseudomonad.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Iron,
http://linkedlifedata.com/resource/pubmed/chemical/Iron Chelating Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Phenols,
http://linkedlifedata.com/resource/pubmed/chemical/Siderophores,
http://linkedlifedata.com/resource/pubmed/chemical/Succinates,
http://linkedlifedata.com/resource/pubmed/chemical/Succinic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/pyochelin
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-1287
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
135
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1479-87
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pubmed:dateRevised |
2005-1-21
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pubmed:meshHeading |
pubmed-meshheading:2533244-Iron,
pubmed-meshheading:2533244-Iron Chelating Agents,
pubmed-meshheading:2533244-Phenols,
pubmed-meshheading:2533244-Pseudomonas,
pubmed-meshheading:2533244-Siderophores,
pubmed-meshheading:2533244-Structure-Activity Relationship,
pubmed-meshheading:2533244-Succinates,
pubmed-meshheading:2533244-Succinic Acid,
pubmed-meshheading:2533244-Thiazoles
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pubmed:year |
1989
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pubmed:articleTitle |
Cepabactin from Pseudomonas cepacia, a new type of siderophore.
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pubmed:affiliation |
Institut de Biologie Moléculaire et Cellulaire du Centre National de la Recherche Scientifique, Strasbourg, France.
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pubmed:publicationType |
Journal Article
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