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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1989-12-20
|
| pubmed:abstractText |
Familial Mediterranean fever is an autosomal recessively inherited disorder of unknown cause characterized by recurrent attacks of inflammation, involving mainly the peritoneum, pleura, synovia, and skin. Based on a phenotype analysis, we propose that its manifestations may be related to a genetic defect in one of the family of lipocortin proteins. Evidence is presented supporting an abnormality in the first step of prostaglandin/leukotriene synthesis.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0148-7299
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
34
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
163-7
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:2530899-Annexins,
pubmed-meshheading:2530899-Calcium-Binding Proteins,
pubmed-meshheading:2530899-Diet,
pubmed-meshheading:2530899-Estrogens,
pubmed-meshheading:2530899-Familial Mediterranean Fever,
pubmed-meshheading:2530899-Genes, Recessive,
pubmed-meshheading:2530899-Humans,
pubmed-meshheading:2530899-Phospholipases
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
Hypothesis: familial Mediterranean fever--a genetic disorder of the lipocortin family?
|
| pubmed:affiliation |
Medical Genetics Birth Defects Center, Ahmanson Pediatric Center, Los Angeles, CA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|